Modularity and directionality in genetic interaction maps

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Modularity and directionality in genetic interaction maps

MOTIVATION Genetic interactions between genes reflect functional relationships caused by a wide range of molecular mechanisms. Large-scale genetic interaction assays lead to a wealth of information about the functional relations between genes. However, the vast number of observed interactions, along with experimental noise, makes the interpretation of such assays a major challenge. RESULTS He...

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ژورنال

عنوان ژورنال: Bioinformatics

سال: 2010

ISSN: 1367-4803,1460-2059

DOI: 10.1093/bioinformatics/btq197